A wound that won’t heal can be due to simple causes, such as rubbing, scratching, or repeated irritation, but it can also be a sign of infection, poor circulation, diabetes, or, in some cases, skin cancer. In this article, you’ll find out what signs to watch for, when to schedule a dermatology appointment, and in what situations it’s best to seek urgent medical attention.
Before you read: This article provides general medical information to help you recognize signs that might warrant a dermatological evaluation. It is not a substitute for a medical consultation and does not allow for online diagnosis. If you have a lesion that changes, bleeds, hurts, grows rapidly, or is accompanied by general symptoms, consult your doctor.
What does this sign mean?
A non-healing wound is an area of open, eroded, ulcerated, or scabbed skin that is not progressing toward the expected healing. It may appear as a sore, a crack that won’t close, a scab that falls off and forms again, or an injury that bleeds easily.
Not all wounds heal at the same rate. Healing depends on depth, location, circulation, the presence of infection, friction, underlying conditions such as diabetes, and the overall condition of the skin (among other factors). Chronic wounds are described as those that do not progress through a normal, orderly, and timely sequence of repair. Bowers-2020
As a general guideline, DermNet defines chronic wounds as those that do not appear to follow the normal healing process in less than 4 weeks. However, the decision to seek medical advice depends not only on time: it also matters if the wound grows, bleeds, is painful, oozes, has a foul odor, or appears over an old scar. DermNet-2023
A wound that doesn’t heal shouldn’t cause panic, but it shouldn’t be ignored either. Most causes have an explanation and treatment, but some persistent injuries require early diagnosis.
Common and generally less serious causes
In many cases, a wound takes a long time to heal because of ongoing irritation. This can be caused by scratching, rubbing against clothing, pressure from footwear, moisture, friction, or repeated picking at the scab.
Slow healing can also occur when the wound is in an area with reduced circulation, such as the legs or feet. Contributing factors in leg ulcers include vascular disease, edema, diabetes, smoking, malnutrition, prior radiation therapy, and decreased mobility. Oakley-2016
A common cause of leg ulcers is chronic venous insufficiency. It can be accompanied by swelling, brown spots, venous eczema, heaviness, and ulcers around the ankle; DermNet describes chronic venous insufficiency as a common cause of leg ulcers. Oakley-2016
On the feet, especially if there is diabetes, loss of sensation, or circulatory problems, a small wound can go unnoticed and become deeper. Diabetic foot ulcers are related to neuropathy, peripheral arterial disease, and repeated pressure on certain areas of the foot. Bowers-2020
Pressure injuries can also be slow to heal, especially in people with reduced mobility. They often appear over bony prominences such as heels, hips, sacrum, or elbows; pressure ulcers are associated with sustained pressure on specific points of the skin. Bowers-2020
Important causes that should not be overlooked
A persistent wound isn’t always a common wound. In some cases, it may be necessary to rule out skin cancer, especially if it bleeds, repeatedly crusts over, grows slowly, is painless but doesn’t heal, appears in sun-exposed areas, or develops over an old scar.
- Basal cell carcinoma can present as a sore that does not heal or that heals and then reopens, according to the American Academy of Dermatology. AAD-2025
- Squamous cell carcinoma can also appear as a lesion in a pre-existing wound, sore, or scar. The American Academy of Dermatology recommends paying attention to growths, lumps, or bleeding in scars and wounds that do not heal. AAD-2026
- Although less common, melanoma can also appear as a lesion that bleeds, changes, or fails to heal. The American Academy of Dermatology includes a sore that does not heal or that heals and recurs among the signs that should raise concern when checking the skin. AAD-2026
- In chronic leg ulcers that do not improve despite appropriate treatment, a biopsy may be necessary. In a multicenter study of chronic leg ulcers resistant to 3 months or more of treatment, skin cancer was found in 10.4% of the ulcers evaluated at specialized dermatology centers. Senet-2012 .
- Persistent wounds can also result from chronic infections, foreign bodies, inflammatory diseases, vasculitis, or pyoderma gangrenosum. Some inflammatory causes of ulcers may require deep biopsy of the ulcer margin and further studies (Oakley, 2016).
Signs that you should consult a dermatologist
Consult a dermatology specialist if you notice any of these situations:
- The wound shows no clear improvement after 2 to 4 weeks.
- The wound heals partially, but reopens.
- It bleeds easily or forms repeated scabs.
- It grows, changes shape, rises, or becomes harder.
- It has irregular, shiny, pearly, raised or very inflamed edges.
- It appears over an old scar, a previous burn, or an area of radiotherapy.
- It is on the face, ears, scalp, lips, hands, genitals, feet or under/around a nail.
- There is persistent pain, localized itching, or sensitivity in the same spot.
- There is discharge, a bad odor, or an increase in the size of the wound.
- You have diabetes, poor circulation, immunosuppression, a transplant, a history of skin cancer, or previous chronic wounds.
Signs to seek urgent medical attention
Seek urgent medical attention if the wound is accompanied by:
- Fever, chills, or general malaise.
- Redness that spreads rapidly.
- Intense pain or pain that increases markedly.
- Progressive swelling, significant heat, or tight skin around the affected area.
- Abundant pus, intense bad odor, or increasing discharge.
- Red or purple lines extending from the wound.
- Black, purplish skin, extensive blisters, or loss of sensation.
- Deep wound from a bite, dirty object, foreign body or major trauma.
- A wound in a person with diabetes, immunosuppression, or poor circulation, especially if it is on the foot.
Cellulitis can cause painful, red, warm, swollen, and tender skin, and the CDC recommends seeking immediate medical attention if the red area spreads rapidly or if fever or chills develop. CDC-2025
The NHS also considers high fever, chills, rapid breathing, confusion, dizziness, cold or clammy skin, and purple spots to be warning signs, as these can indicate serious complications from a skin infection. NHS-2024
Consult a doctor if the wound does not improve, bleeds, grows larger, is painful, forms repeated scabs, or appears over a scar. Seek urgent care if there is fever, spreading redness, severe pain, pus, general malaise, or if the wound is on a foot with diabetes or poor circulation.
What can you do while you wait for your appointment?
While you wait for the assessment, you can follow these general measures:
- Avoid manipulating the wound. Do not pick at scabs, do not scratch it, and do not try to «burn» it or dry it with alcohol, lemon, hydrogen peroxide, repeated iodine, or other irritating remedies.
- You can take well-lit photos every few days, ideally dated and with a size reference, such as a clean ruler. This helps to see if the lesion grows, changes, or bleeds.
- For superficial wounds, the American Academy of Dermatology recommends gently washing with mild soap and water and covering with a clean bandage (AAD-2025).
- Do not use topical antibiotics, strong corticosteroids, combination creams, or prescription medications without a doctor’s prescription.
- Protect the affected area from the sun, especially if it’s on the face, scalp, arms, hands, or legs. If the wound is on the foot or in a pressure area, avoid friction and don’t walk long distances on it until you have medical advice.
- If you have diabetes or circulatory problems, don’t wait for it to «close on its own.» Wounds on feet or legs require earlier evaluation because they can deepen or become infected more easily. Bowers-2020
What does a dermatologist usually do?
The dermatologist typically examines the lesion directly, assesses the surrounding skin, and reviews factors that may be hindering healing. Depending on the case, they may use dermatoscopy, clinical photography, wound measurement, culture if infection is suspected, or studies to evaluate circulation.
If the lesion appears atypical, bleeds, grows, does not respond to appropriate care, or raises suspicion of skin cancer, a biopsy may be necessary. Atypical, non-healing wounds should be biopsied. Bowers-2020
A biopsy allows a skin sample to be analyzed under a microscope. This helps to differentiate between inflammation, infection, vascular ulcer, autoimmune disease, drug reaction, or skin cancer.
In leg ulcers, a biopsy of the ulcer margin is indicated when there is diagnostic uncertainty or failure of healing. DermNet-2023
Treatment will depend on the cause. It may include advanced wound care, pressure offloading, compression if indicated and with good circulation, infection management, treatment of eczema or inflammation, vascular bypass, dermatologic surgery, or close follow-up.
Bibliography and sources
- Bowers S, Franco E. Chronic wounds: evaluation and management. Am Fam Physician . 2020;101(3):159-166. PMID: 32003952. Available at: https://pubmed.ncbi.nlm.nih.gov/32003952/
- DermNet NZ. Abnormal wound healing [Internet] . DermNet NZ; 2023 [citado 2026 May 10] . Available at: https://dermnetnz.org/cme/wound-healing/abnormal-wound-healing
- Oakley A. Differential diagnosis of leg ulcer [Internet] . DermNet NZ; 2016 [actualizado 2023; citado 2026 May 10] . Available at: https://dermnetnz.org/topics/differential-diagnosis-of-leg-ulcer
- American Academy of Dermatology Association. Basal cell carcinoma: from symptoms to treatments [Internet] . American Academy of Dermatology Association; 2025 [citado 2026 May 10] . Available at: https://www.aad.org/public/diseases/skin-cancer/basal-cell-carcinoma
- American Academy of Dermatology Association. Squamous cell carcinoma: from symptoms to treatments [Internet] . American Academy of Dermatology Association; 2026 [citado 2026 May 10] . Available at: https://www.aad.org/public/diseases/skin-cancer/squamous-cell-carcinoma
- American Academy of Dermatology Association. Melanoma: signs and symptoms [Internet] . American Academy of Dermatology Association; [citado 2026 May 10] . Available at: https://www.aad.org/public/diseases/skin-cancer/types/common/melanoma/symptoms
- Senet P, Combemale P, Debure C, Baudot N, Machet L, Lok C, et al. Malignancy and chronic leg ulcers: the value of systematic wound biopsies: a prospective, multicenter, cross-sectional study. Arch Dermatol . 2012;148(6):704-708. doi:10.1001/archdermatol.2011.3362. PMID: 22772403. Available at: https://pubmed.ncbi.nlm.nih.gov/22772403/
- DermNet NZ. Leg ulcers: wound healing [Internet] . DermNet NZ; 2023 [citado 2026 May 10] . Available at: https://dermnetnz.org/cme/wound-healing/leg-ulcers-cme
- Centers for Disease Control and Prevention. About cellulitis [Internet] . Atlanta: CDC; 2025 Aug 5 [citado 2026 May 10] . Available at: https://www.cdc.gov/group-a-strep/about/cellulitis.html
- National Health Service. Cellulitis [Internet] . NHS; 2024 Apr 18 [citado 2026 May 10] . Available at: https://www.nhs.uk/conditions/cellulitis/
- American Academy of Dermatology Association. Minimize a scar: proper wound care tips from dermatologists [Internet] . American Academy of Dermatology Association; 2025 Jul 2 [citado 2026 May 10] . Available at: https://www.aad.org/public/everyday-care/injured-skin/burns/wound-care-minimize-scars
- American Academy of Dermatology Association. Skin biopsy: dermatologist-recommended wound care [Internet] . American Academy of Dermatology Association; 2022 Nov 29 [citado 2026 May 10] . Available at: https://www.aad.org/public/diseases/az/skin-biopsy-wound-care
Categories: A wound that does not heal · For everyone · Warning signs

Content reviewed by
Dr. Rodolfo Suárez
Médico Patólogo y Dermatólogo Master en Patología Cutánea Avanzada
- Published
- September 18, 2026
- Updated
- September 23, 2026
Medically reviewed by specialists
Our content is based on current scientific evidence and clinical protocols.