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Eccrine poroma

Published: September 18, 2026Updated: September 18, 2026

Important: Informational content intended for healthcare professionals. It does not replace clinical evaluation or establish a doctor-patient relationship.

Overview

  • Definition and synonyms
    • A benign adnexal tumor originating from the terminal duct of the sweat gland (acrosyringium), composed of poroid cells with ductal differentiation; it belongs to the group of poroid neoplasms (classic eccrine poroma + simple hydroacanthoma, dermal poroma/dermal duct tumor, poroid hidradenoma). Sawaya 2014 , Syed 2024 , Chen 2006
  • Common synonyms:
    • Eccrine poroma
    • Poroma (just) / poroid tumor
    • “Acrospiroma” (historical term, now used less) Sawaya 2014
    • Today it is known that many poromas also show apocrine differentiation; for this reason, some authors simply refer to them as “poromas” rather than “eccrine.” Sawaya 2014 , Langbein 2008
  • History
    • First described in 1956 by Goldman, Pinkus, and Rogin as “eccrine poroma; tumors exhibiting features of the epidermal sweat duct unit”. Goldman 1956
  • Epidemiology (summary)
    • Sweat gland tumors account for approximately 1% of primary skin neoplasms; poromas represent approximately 10% of these sweat gland tumors. Syed 2024 , Efared 2024
    • It primarily affects adults and the elderly (4th–8th decade), but has been described in virtually any age. Sawaya 2014 , Kyrmanidou 2023
    • No clear gender predominance. Syed 2024
    • Classic location: palms and soles (acral areas rich in eccrine glands), but it can appear on any cutaneous area (face, scalp, trunk, limbs, periungual region, eyelid, auricle, groin, etc.). Sawaya 2014 , Shah 2018 , Wang 2021
    • Usually solitary , although forms with multiple lesions exist (“poromatosis”), often associated with prior radiotherapy or immunosuppression. Syed 2024 , Kyrmanidou 2023
  • Codes: It does not have its own code; it is coded as benign skin neoplasm of sweat glands according to location:
    • ICD-10-CM: D23.x (Other benign skin tumors of [sitio] ) – includes benign sweat gland tumors.
    • ICD-11: within Benign neoplasms of epidermal appendages (2F22) ; morphology: Poroma, NOS (XH8N28) .
  • Diagnostic checklist (quick)
    • Clinic
      • Solitary, nodular/plaque lesion, slow-growing, usually <2 cm
      • Common location is acral, but consider any cutaneous site
      • Symptomatic only from friction/trauma (mild pain, bleeding)
      • Absence of recent explosive changes (if present → suspect malignancy)
    • Dermatoscopy
      • Polymorphic vascular pattern (glomerular, hairpin, linear)
      • White-pink or pink-orange areas without structure
      • In pigmented variants: blue-green networks/nests, ovoid structures, atypical milia-like cysts
    • Histology (biopsy)
      • Well-defined lesion, connected to the epidermis (juxtaepidermal poroma)
      • Cuboidal poroid cells with little atypia
      • Intratumoral ducts with PAS+ cuticle
      • Fibrovascular stroma, without frank infiltration or extensive necrosis
      • Low Ki-67, without marked atypia or lymphovascular invasion (if immunological is performed)
      • If any of these points “fail” in the sense of malignancy (marked nuclear atypia, infiltrative pattern, high Ki-67, necrosis, vascular invasion) → think of porocarcinoma and manage as a malignant adnexal tumor.

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